Research

The science of gratitude and Its effects on your brain

Emilie Mauricio

October 29, 2025

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8 min read

In an era marked by stress and uncertainty, cultivating gratitude can be a powerful tool for improving mental well-being. Research shows that practicing gratitude not only boosts mood but also rewires the brain for greater happiness and resilience.

A man sitting in a coffee shop, writing in a gratitude journal with a pen and notebook on a table.

Studies have revealed the remarkable impact of gratitude on brain function. For instance, a study published in the journal NeuroImage found that expressing gratitude activates areas of the brain associated with the release of dopamine, a neurotransmitter linked to feelings of pleasure and reward. This suggests that practicing gratitude can stimulate the brain's reward system, leading to increased feelings of happiness and contentment.

Furthermore, research conducted at the University of California, Berkeley, found that individuals who regularly practiced gratitude showed increased activity in the prefrontal cortex, a region of the brain associated with decision-making, emotional regulation, and goal-setting. This suggests that gratitude may enhance cognitive function and improve overall mental resilience.

Beyond its effects on brain function, gratitude has been linked to numerous physical and psychological benefits. According to a study published in the Journal of Personality and Social Psychology, individuals who kept a gratitude journal reported higher levels of optimism, better sleep quality, and reduced symptoms of depression compared to those who did not practice gratitude regularly.

Moreover, research conducted at Harvard Medical School found that individuals who expressed gratitude experienced lower levels of stress hormones such as cortisol, leading to improved immune function and better overall health.

Incorporating gratitude into your daily routine is simple yet transformative. Start by keeping a gratitude journal and writing down three things you are grateful for each day. Take time to savor and reflect on these moments of gratitude, allowing them to deepen your sense of appreciation and well-being.

As you cultivate a habit of gratitude, you may find yourself experiencing greater joy, resilience, and fulfillment in life. By harnessing the science of gratitude, you can unlock the transformative power of appreciation and cultivate a more positive and resilient mindset.

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